Alveolar Overdistension as a Cause of Lung Injury: Differences among Three Animal Species
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چکیده
منابع مشابه
Alveolar Overdistension as a Cause of Lung Injury: Differences among Three Animal Species
This study analyses characteristics of lung injuries produced by alveolar overdistension in three animal species. Mechanical ventilation at normal tidal volume (10 mL/Kg) and high tidal volume (50 mL/Kg) was applied for 30 min in each species. Data were gathered on wet/dry weight ratio, histological score, and area of alveolar collapse. Five out of six rabbits with high tidal volume developed t...
متن کاملIntermittent alveolar overdistension for 30 or 240 minutes does not produce acute lung injury in normal pig lung.
BACKGROUND The objective is to study whether alveolar overdistension can induce acute lung injury in pigs as assessed by analysis of respiratory and histological parameters and inflammatory markers. MATERIALS AND METHODS Experimental study, using mixed-breed pigs. Animals were assigned to one of the following groups: Control Group (CG) (n = 5), applying mechanical ventilation with tidal volum...
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ژورنال
عنوان ژورنال: The Scientific World Journal
سال: 2012
ISSN: 1537-744X
DOI: 10.1100/2012/985923